Interleukin 13 (IL-13) (PE), IgG1, Clone: [1.B2.1], Rat, Monoclonal
Biozol Catalog Number:
USB-I8435-05-PE
Supplier Catalog Number:
I8435-05-PE
Alternative Catalog Number:
USB-I8435-05-PE-100
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Immunogen:
Purified recombinant human IL-13
IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy. Applications: Suitable for use in Neutralizing, FLISA, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by researcher. Hybridoma: Rat spleen cells fused with P3X63-AG8.653 myeloma Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[1.B2.1]
Isotype:
IgG1
Purity:
Purified by Protein A/G affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with R-Phycoerythrin (PE).
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