IP3R1 (IP3 Receptor Isoform 1, IP3R 1, IP3R, InsP3R1, Inositol 1,4,5-trisphosphate Receptor Type 1, ITPR1, SCA15, SCA16, Type 1 inositol 1,4,5-trisphosphate Receptor, Type 1 InsP3 Receptor) (Not for Export EU), Rabbit
Biozol Catalog Number:
USB-I8470-04B
Supplier Catalog Number:
I8470-04B
Alternative Catalog Number:
USB-I8470-04B-100
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Immunogen:
Synthetic peptide corresponding to the N-terminal of human IP3 Receptor 1. Species Sequence Homology: canine and rat.
IP3 Receptor 1 is an intracellular channel that when stimulated by inositol 1,4,5-triphosphate mediates the release of calcium from the endoplasmic reticulum. Defects within the gene ITPR1 cause a group of cerebellar disorders known as spinocerebellar ataxia type 15 (SCA15). This receptor is widely expressed in tissue. Applications: Suitable for use in Western Blot and Immunohistochemisty. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 Immunohistochemistry (Paraffin): 1:100 Optimal dilutions to be determined by the researcher. Positive Control: C2C12 cell lysates Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
