| Lasalocid is a polyether ionophore with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase (including lipid bilayer membranes). Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine. Synonyms: 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-Ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic Acid Sodium Salt, 6-[7-[5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2,3-cresotic Acid Monosodium Salt, (3R*,4S*,5S*,7R*),3S*,5S*],5alpha,6beta]]-6-[7-[5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic Acid Monosodium Salt, Avatec, Bovatec, Lasalocid Sodium, Lasalocid Sodium Salt, MT 2007, NSC 243046, Ro 2-2985, Sodium Lasalocid, Sodium Lasalocid A CAS No: 25999-20-6 Molecular Formula: C34H53NaO8 Molecular Weight: 612.77 Appearance: Off-white to pale beige solid Purity: 95% Solubility: Acetonitrile (Slightly, heated), Methanol (Slightly) Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol = 9:1, Visualized with UV and KMnO4, Single spot, Rf=0.55 Specific Rotation: -28.6 (c=0.2, Methanol) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere. |
