Leflunomide-d4 (5-Methylisoxazole-4-[4-trifluoromethylcarboxanilide]-d4), CAS [[1189987-23-2]]

Product Overview

• Article Name: Leflunomide-d4 (5-Methylisoxazole-4-[4-trifluoromethylcarboxanilide]-d4), CAS [[1189987-23-2]]
• Biozol Catalog Number: USB-L1662-92D
• Supplier Catalog Number: L1662-92D
• Alternative Catalog Number: USB-L1662-92D-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Source: Synthetic Purity: ~90% Form: Supplied as an off-white crystalline solid Melting Point: 159-161C Solubility: Chloroform, Methanol Method for Determining Identity: Proton NMR and Mass Spectroscopic Analysis. TLC Conditions: SiO2: Hexane: Ethyl Acetate, 3:2, Visualized with UV and KMnO4, Single spot, Rf=0.6. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 274.23
• Purity: ~90%
• Form: Supplied as an off-white crystalline solid
• CAS Number: [1189987-23-2]