Levofloxacin Hemihydrate ((-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, Hemihydrate), CAS [[138199-71-0]]

Product Overview

• Article Name: Levofloxacin Hemihydrate ((-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, Hemihydrate), CAS [[138199-71-0]]
• Biozol Catalog Number: USB-L2051-35
• Supplier Catalog Number: L2051-35
• Alternative Catalog Number: USB-L2051-35-100
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Levofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class[1][2] and is used to treat severe or life-threatening bacterial infections or bacterial infections that have failed to respond to other antibiotic classes.[3][4] It is sold under various brand names, such as Levaquin and Tavanic, the most common. In form of ophthalmic solutions it is known as Oftaquix, Quixin and Iquix. Levofloxacin is a chiral fluorinated carboxyquinolone. Investigation of ofloxacin, an older drug that is the racemic mixture, found that the l form [the (-)-(S) enantiomer] is more active. This specific component is levofloxacin.[5][6] Levofloxacin interacts with a number of other drugs, as well as a number of herbal and natural supplements. Such interactions increase the risk of cardiotoxicity and arrhythmias, anticoagulation, the formation of non-absorbable complexes, as well as increasing the risk of toxicity.[7] Levofloxacin is associated with a number of serious and life-threatening adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Such reactions may manifest long after therapy had been completed and in severe cases may result in life-long disabilities. Hepatoxicity has also been reported with the use of levofloxacin.[8][9] Melting Point: As Reported Solubility: As Reported Method for Determining Identity: Proton NMR Spectroscopic Analysis TLC Conditions: As Reported Specific Rotation: As Reported Water Content: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

Product Properties

• Molecular Weight: 370.38
• Purity: ~90%
• CAS Number: [138199-71-0]