Macrophage Inflammatory Protein 5, Recombinant, Human (MIP5, CCL15)

Product Overview

• Article Name: Macrophage Inflammatory Protein 5, Recombinant, Human (MIP5, CCL15)
• Biozol Catalog Number: USB-M1202-73H
• Supplier Catalog Number: M1202-73H
• Alternative Catalog Number: USB-M1202-73H-25,USB-M1202-73H-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

MIP-5 is a CC chemokine that is expressed in the heart, skeletal muscle and adrenal gland. MIP-5 primarily signals through the CCR1 receptor, but has also been found to bind to CCR3. MIP-5 is chemotactic towards T cells and monocytes. Recombinant human MIP-5 is a 10.1kD protein containing 92 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Recombinant protein corresponding to 92aa from human Macrophage Inflammatory Protein 5 expressed in E. coli. Molecular Weight: ~10.1kD Biological Activity: Determined by its ability to chemoattract human T lymphocytes using a concentration range of 1-10ng/ml. Amino Acid Sequence: QFTNDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O, 0.1% HSA or BSA. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 10.1
• UniProt: Q16663
• Purity: 98% (SDS-PAGE and HPLC). Endotoxin: 0.1ng/ug (1EU/ug)
• Form: Supplied as a lyophilized powder. Reconstitute with with sterile ddH2O, 0.1% HSA or BSA to 0.1-1mg/ml. Further dilutions can be made into other buffered solutions.