Malate Dehydrogenase 1, Recombinant, Human, aa1-334, His-Tag (MDH1, Cytosolic Malate Dehydrogenase)
Catalog Number:
USB-M2115-35B
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| Article Name: | Malate Dehydrogenase 1, Recombinant, Human, aa1-334, His-Tag (MDH1, Cytosolic Malate Dehydrogenase) |
| Biozol Catalog Number: | USB-M2115-35B |
| Supplier Catalog Number: | M2115-35B |
| Alternative Catalog Number: | USB-M2115-35B-100,USB-M2115-35B-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| MDH1 is one of the two malate dehydrogenases. Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. In particular, MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. This protein also regulates p53-dependent cell-cycle arrest and apoptosis in response to glucose deprivation. Recombinant protein corresponding to aa1-334 of human recombinant MDH1 protein, fused to His-tag at C-terminus, expressed in E.coli. Amino Acid Sequence: MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC ALPLLKDVIATDKEDVAFKD LDVAILVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFVTTVQQR GAAVIKARKL SSAMSAAKAI CDHVRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV EGLPINDFSR EKMDLTAKEL TEEKESAFEF LSSALEHHHH HH Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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