MTAP, Recombinant, Human, GST-Tag (methylthioadenosine phosphorylase, 5-methylthioadenosine phosphorylase, c86fus, MSAP, MTAPase, MTA Phosphorylase, S-methyl-5-thioadenosine Phosphorylase)
Catalog Number:
USB-M2344-97
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| Article Name: | MTAP, Recombinant, Human, GST-Tag (methylthioadenosine phosphorylase, 5-methylthioadenosine phosphorylase, c86fus, MSAP, MTAPase, MTA Phosphorylase, S-methyl-5-thioadenosine Phosphorylase) |
| Biozol Catalog Number: | USB-M2344-97 |
| Supplier Catalog Number: | M2344-97 |
| Alternative Catalog Number: | USB-M2344-97-50 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| MTAP (Methylthioadenosine phosphorylase) is important in polyamine metabolism and for the salvage of both adenine and methionine. It is involved in the metabolism of MeSAdo (methylthioadenosine), a by-product of the synthesis of the polyamines spermidine and spermine. MTAP is deficient in many cancers because the MTAP gene is co-deleted with the tumor suppressor p16. Source: Recombinant human MTAP, aa2-end, with N-terminal GST tag, expressed in E. coli. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months. |
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