MARK4, NT (MAP/microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S), Rabbit
Catalog Number:
USB-M2408-01N
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| Article Name: | MARK4, NT (MAP/microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S), Rabbit |
| Biozol Catalog Number: | USB-M2408-01N |
| Supplier Catalog Number: | M2408-01N |
| Alternative Catalog Number: | USB-M2408-01N-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC |
| Immunogen: | Synthetic peptide selected from the N-terminal region of human MARK4 (KLH). |
| MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain. RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6-kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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