Masitinib, Free Base (AB-1010), CAS [[790299-79-5]]

Product Overview

• Article Name: Masitinib, Free Base (AB-1010), CAS [[790299-79-5]]
• Biozol Catalog Number: USB-M2412-27
• Supplier Catalog Number: M2412-27
• Alternative Catalog Number: USB-M2412-27-5,USB-M2412-27-10,USB-M2412-27-25
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Masitinib mesylate (AB1010) is a protein tyrosine kinase inhibitor. In vitro it has greater activity and selectivity than imatinib mesylate against the wild-type c-Kit receptor and the mutated form in the juxtamembrane region. It also inhibits the PDGF and FGFR3 receptors. Synonyms: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide, AB-1010, Kinavet, Masivet CAS No: 790299-79-5 Molecular Formula: C28H30N6OS Molecular Weight: 498.64 Appearance: Off-white to pale, yellow powder. Purity: 99% (HPLC), 99% (TLC) Melting Point: 98-122C Solubility: Soluble in DMSO at 200mg/ml, very poorly soluble in ethanol or water, maximum solubility in plain water is estimated to be about 10-20uM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 498.64
• Purity: 99% (HPLC), 99% (TLC)
• Form: Off-white to pale, yellow powder.
• CAS Number: [790299-79-5]