Recombinant protein corresponding to human MCP-3 expressed in E. coli.
Human macrophage/monocyte chemotactic protein-3 (MCP-3) is a 8.5kD protein containing 76 amino acids residues. It plays an important role in the inflammatory response of blood monocytes, tissue macrophages, and eosinophils. The gene encoding this protein encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. Applications: Suitable for use in Neutralization and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Produced in C3H/HeJ mice. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[8.PP.8]
Isotype:
IgG1
Purity:
Purified by Protein A affinity chromatography from ascites. Endotoxin: 1EU/mg
Form:
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
* VAT and and shipping costs not included. Errors and price changes excepted
