MD-1 (22-25kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS. Applications: Suitable for use in Flow Cytometry and Functional studies. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10 Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[MD113]
Purity:
Purified by Protein G affinity chromatography.
Form:
Supplied as a liquid in PBS, 0.02% sodium azide, 0.1% BSA.
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