MEK1 Inhibitor (PD98059, 2-amino-3-methoxyflavone), CAS [[167869-21-8]]
Biozol Catalog Number:
USB-M2865-17C
Supplier Catalog Number:
M2865-17C
Alternative Catalog Number:
USB-M2865-17C-5
Manufacturer:
US Biological
Category:
Molekularbiologie
Potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. IC50 values for PD 98059-induced effects are in the 1-20uM range for many assays, it is somewhat weaker in inhibiting cell growth in monolayers or agar for some cell lines. Solubility: Soluble in DMSO. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
267.28
Purity:
~99%
Form:
Supplied as a pale yellow powder.
CAS Number:
[167869-21-8]
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