Synthetic peptide corresponding to the internal region of the human Melatonin Receptor 1B.
MTNR1b is a Melatonin Receptor that mediates the effects of melatonin in the retina and the photoperiodic control of neuroendocrine functions. It may also be involved in melatonin-induced immune enhancement. MTNR1b has been reported in adipose, brain, eye, and ovary. An EST has been isolated from an eye tissue library. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:100 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Human brain Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.