Midkine, Recombinant, Human (MDK, MK, Neurite Growth Promoting Factor-2, NEGF-2)

Catalog Number: USB-M3896-03
Article Name: Midkine, Recombinant, Human (MDK, MK, Neurite Growth Promoting Factor-2, NEGF-2)
Biozol Catalog Number: USB-M3896-03
Supplier Catalog Number: M3896-03
Alternative Catalog Number: USB-M3896-03-100,USB-M3896-03-500
Manufacturer: US Biological
Category: Molekularbiologie
Midkine, also known as Neurite Growth-promoting Factor 2, is a basic heparin-binding growth factor of low molecular weight, a member of the NEGF family whose founding member is pleiotrophin. This protein exhibits neurite outgrowth-promoting activity and may play a role in nervous system development and/or maintenance. Midkine is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. Recombinant human Midkine protein, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography. Source: Recombinant protein corresponding to aa21-143 human Midkine with a His-tag, expressed in E. coli. Accession/Uniprot: NP_002382. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MVAKKKDKVK KGGPGSECAE WAWGPCTPSS KDCGVGFREG TCGAQTQRIR CRVPCNWKKE FGADCKYKFE NWGACDGGTG TKVRQGTLKK ARYNAQCQET IRVTKPCTPK TKAKAKAKKG KGKD Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for 6 months at -20C after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight: 15.7
NCBI: 002382
Purity: 90% by SDS-PAGE under reducing conditions and visualized by coomassie blue stain. Endotoxin: 1EU/ug (LAL)
Form: Supplied as liquid in 20mM Tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 2mM DTT, 20% glycerol.