NCoR2, Recombinant, Human, GST-Tag (SMRT, Nuclear Receptor Co-Repressor)

Product Overview

• Article Name: NCoR2, Recombinant, Human, GST-Tag (SMRT, Nuclear Receptor Co-Repressor)
• Biozol Catalog Number: USB-N0555-05
• Supplier Catalog Number: N0555-05
• Alternative Catalog Number: USB-N0555-05-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

NcoR2 (nuclear receptor co-repressor) is a transcriptional corepressor that plays an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain (DAD) of NCOR2/SMRT is required for activation of the otherwise inert deacetylase. Recombinant human NCoR2 contains aa395-489 with an N-terminal GST tag (GenBank Accession No. NM_006312). Applications: Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.

Product Properties

• Molecular Weight: 39
• NCBI: 006312
• UniProt: Q9Y618
• Purity: > 60% by SDS-PAGE
• Form: Supplied as a liquid in 50mM Tris HCl, pH 8.0, 138mM sodium chloride, 0.1% Tween 20, 10% glycerol.