Partial recombinant protein corresponding to aa22-131 from human Neuropilin-1 with a GST tag.
The antibody is made against the membrane-bound isoform 1 of Neuropilin-1. It is a receptor involved in the development of the cardiovascular systerm, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It binds both vascular endothelial growth factor (VEGF) and semaphorin family members. Isoform 1 is expressed by blood vessels of different tissues. In the developing embryo it is predominantly found in the nervous system. In adult tissues, it is highly expressed in heart and placenta, moderately expressed in lung, liver and skeletal muscle, kidney and pancreas, and low in adult brain. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
