The p75 low affinity human Nerve Growth Factor receptor (TNFRSF16) is expressed on a variety of tissue types including a subset of splenic and nodal lymphocytes. Presence of this receptor supports uptake of intracellular calcium, but not mobilization(3). Its immunological role has not yet been elucidated. NGFR-muIg fusion protein binds to recombinant NGFb coated plates in EIA Human NGFR(p75)-muIg Fusion Protein Molecular Structure: A soluble fusion protein consisting of the extracellular (195aa) domain of human NGFR fused to murine IgG2a Fc (233aa). N-Teminal Sequence: (29)KEACP Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
Purified by affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.5, 0.2% BSA, 0.04% sodium azide, 5% glycerol. Labeled with Biotin.
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