Nectin-1, also called PVRL1, PRR1, Vec C, CD111, HveC and HigR, is an adhesion molecule widely expressed in cell lines of different lineages, including hematopoietic cells, neuronal cells, endothelial and epithelial cells. Nectin-1 belongs to a new family of immunoglobulin-like molecules that includes four members (Nectin-1, -2, -3 and CD155). Nectin-1 gene is localized to human chromosome 11q23-q24, and encodes at least two different transmembrane isoforms. Nectin-1 is a pan alpha herpes virus entry receptor that mediates entry of many HSV1 and HSV-2 strains, bovine Herpes virus1 (BHV-1) and porcine pseudorabies virus (PRV). Applications: Suitable for use in Immunoprecipitation, Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilutions: Immunoprecipitation (Native): 5-10ug/reaction Western Blot: 0.1-1ug/ml Flow Cytometry: 5-10ug/ml ELISA: 0.1-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[6A139]
Purity:
Purified by Protein A affinity chromatography
Form:
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Biotin.
* VAT and and shipping costs not included. Errors and price changes excepted
