NPXR1, Mouse, Control Peptide (Neuronal Pentraxin 1 Receptor)
Biozol Catalog Number:
USB-N5379-14A
Supplier Catalog Number:
N5379-14A
Alternative Catalog Number:
USB-N5379-14A-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
ELISA
Pentraxins are a family of proteins emerging from genes that are conserved in their carboxy-terminal halves a pentraxin domain and are prototypical acute phase proteins with acquired novel amino-terminal domains. Pentraxins, include C reactive protein (CRP) and Serum Amyloid P component (SAP), which serve as indicators of inflammatory reactions as a result of the exposure of liver cells to cytokines, mainly interleukin-6 (IL-6). Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPXR1 (Neuronal Pentraxin Receptor 1) a 493aa protein in mouse, 494 in rat, and 499aa in human. The predominant form of NPXR contains a putative NH2 terminal transmembrane and all forms are glycosylated. It shows 49 and 48% homology with NPX1 and NPX2 respectively. NPXR message is expressed in neuronal regions that express NPX1 and NPX2. Source: 14aa peptide from Mouse NPXR1 (1) Location: ~C-terminus Species Sequence Homology: Human, rat-100%. Applications: Suitable for use in ELISA as a control peptide for N5379-14. Other applications not tested. Recommended Dilution: ELISA: Coat ELISA plates at 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
Purified
Form:
Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
* VAT and and shipping costs not included. Errors and price changes excepted
