NTF4, is a member of a family of neurotrophic factors neurotrophins that control survival and differentiation of mammalian neurons. This protein is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derivedneurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF4-deficient mice only show minor cellular deficits and develop normally to adulthood. Source: Recombinant corresponding to aa81-210 from human NTF4 expressed in E.coli. Amino Acid Sequence: MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A Molecular Weight: ~14.1kD Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
