Nudix-type Motif 21, aa1-227, Recombinant, Human (Nucleoside Diphosphate Linked Moiety X Motif 21, Nudix Motif 21, NUDT21, CFIM25, Cleavage and Polyadenylation Specificity Factor Subunit 5, CPSF5, Cleavage and Polyadenylation Spec
Biozol Catalog Number:
USB-N7400-25B
Supplier Catalog Number:
N7400-25B
Alternative Catalog Number:
USB-N7400-25B-100,USB-N7400-25B-500
Manufacturer:
US Biological
Category:
Molekularbiologie
NUDT21, also known as CPSF5 or CFIm25, is a member of the Nudix hydrolase family of pyrophosphatases. This protein localizes to the paraspeckles and forms a heterodimer with CPSF6 or CPSF7 to comprise the CFIm (mammalian cleavage factor I) complex. NUDT21 is the smaller subunit of the complex and is present in all heterodimer combinations. NUDT21 plays an important role in pre-mRNA 3 cleavage and polyadenylation processing. Source: Recombinant corresponding to human NUDT21, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~28.3kD Sequences of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSVVPPNRSQ TGWPRGVTQF GNKYIQQTKP LTLERTINLY PLTNYTFGTK EPLYEKDSSV AARFQRMREE FDKIGMRRTV EGVLIVHEHR LPHVLLLQLG TTFFKLPGGE LNPGEDEVEG LKRLMTEILG RQDGVLQDWV IDDCIGNWWR PNFEPPQYPY IPAHITKPKE HKKLFLVQLQ EKALFAVPKN YKLVAAPLFE LYDNAPGYGP IISSLPQLLS RFNFIYN Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
