The osteogenic growth peptide OGP (ALKRQGRTLYGFGG) is a key factor in the mechanism of the systemic osteogenic response to local bone marrow injury. OGP level is increased in the serum in vivo during osteogenic reactions in the form of OGP-OGP binding protein complex. When it is applied to pre-osteoblast in vitro, OGP promotes bone cell proliferation and differentiation, which is indicated by increasing ALP Alkaline phosphatase activity. When it is administered in vivo, OGP stimulates osteogenesis and hematopoiesis. Sequence (linear): Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Stable for 12 months at -20C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
95+% HPLC, Mass Spec
Form:
Supplied as a white to off-white lyophilized powder.
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