Oxaliplatin is a a third-generation, diaminocyclohexane-containing platinum anti-cancer drug. It is typically used in combination with fluorouracil (5-FU) and leucovorin, known as FOLFOX, for the treatment of colorectal cancer. The leucovorin-modulated single-agent 5-FU regimens achieved a median overall survival of 15 months or less. Combination regimens of FOLFOX consistently lead to median survivals in the 15-20 month range. Synonyms: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N)[ethanedioato(2-)-O,O]platinum, (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN][ethanedioato(2-)-kO1,kO2]platinum, (1R-trans)-1,2-Cyclohexanediamine Platinum Complex, Dacplat, Eloxatin, Elplat, Lipoxal, Oxalatoplatinum CAS No: 61825-94-3 Molecular Formula: C8H14N2O4Pt Molecular Weight: 397.29 Appearance: White to off-white powder Purity: 99% Elemental Analysis: Calculated: C: 24.19% H: 3.55% N: 7.05% Solubility: Soluble in water at 4mg/ml and DMSO at 20mg/ml, very slightly soluble in methanol, insoluble in ethanol. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C.
Molecular Weight:
397.29
Purity:
99%
Form:
White to off-white powder
CAS Number:
[61825-94-3 63121-00-6]
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