Antitumor and antileukemic agent isolated from the bark of the yew tree, Taxus brevifolia/chinensis. Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibits MT depolymerization, and changes MT dynamics required for mitosis and cell proliferation. Paclitaxel can induce ototoxicity in rats. Botanical Source: Taxus chinensis Synonyms: Abraxane, Genaxol, Genetaxyl, OncoGel, Onxal, Pacliex, (-)-Paclitaxel, Taxol, Yewtaxan, NSC 125973 CAS No: 33069-62-4 Molecular Formula: C47H51NO14 Molecular Weight: 853.92 Purity: 98% (HPLC) Appearance: White powder Melting Point: >212C (dec.) (lit) Method of Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis Water Content: 3% Storage and Stability: Store at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
853.92
CAS Number:
[33069-62-4]
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