PKC412 (4-N-Benzoyl Staurosporine, CGP 41251, Midostaurin), CAS [[120685-11-2]]

Product Overview

• Article Name: PKC412 (4-N-Benzoyl Staurosporine, CGP 41251, Midostaurin), CAS [[120685-11-2]]
• Biozol Catalog Number: USB-P4210-63
• Supplier Catalog Number: P4210-63
• Alternative Catalog Number: USB-P4210-63-1,USB-P4210-63-10,USB-P4210-63-25
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

The staurosporine analog, PKC412, inhibits a variety of serine/threonine and tyrosine kinases including PKC (IC50=50nM), cyclic AMP-dependent protein kinase (IC50=2.4uM), S6 kinase (IC50=5.0uM), and EGFR (epidermal growth factor receptor) tyrosine-kinase activity (IC50=3.0uM). CAS Number: 120685-11-2 Molecular Formula: C35H30N4O4 Molecular Weight: 570.64 Appearance: Supplied as off-white to beige, tan or yellow solid.. Purity: 99% Solubility: Soluble in DMSO at 100mg/ml and in ethanol at 5mg/ml with warming. Very poorly soluble in water, maximum solubility in water is ~10-20uM, buffers, serum or other additives may increase or decrease aqueous solubility. Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 570.64
• Purity: 99%
• Form: Supplied as off-white to beige, tan or yellow solid.
• CAS Number: [120685-11-2]