| Protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). Research indicated that prostratin has potential to be useful in the treatment of HIV as it flushes viral reservoirs in latently infected CD4+ T-cells. Isolated from strathmore weed (Pimelia prostrata Wild), a New Zealand plant toxic to livestock. Synonyms: (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl- 5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one, 12-Deoxyphorbol 13-acetate, 13-O-Acetylphorbol, NSC 623310, Stillingia Factor S7 CAS No: 60857-08-1 Molecular Formula: C22H30O6 Molecular Weight: 390.47 Appearance: White to off-white powder Purity: 98% Solubility: Chloroform (Slightly), DMSO, Ethanol Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Highly irritant to skin and mucous membranes. |
