Retinoic Acid (all-trans Retinoic Acid, Vitamin A Acid, ATRA, Tretinoin), CAS [[302-79-4]]

Product Overview

• Article Name: Retinoic Acid (all-trans Retinoic Acid, Vitamin A Acid, ATRA, Tretinoin), CAS [[302-79-4]]
• Biozol Catalog Number: USB-R1690-01E
• Supplier Catalog Number: R1690-01E
• Alternative Catalog Number: USB-R1690-01E-1,USB-R1690-01E-5,USB-R1690-01E-25
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR), mediates cellular growth and differentiation. Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons. Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, Tretinoin, all-trans-Retinoic acid, ATRA, Vitamin A acid, 15-Apo-beta-caroten-15-oic acid, Aberel, Avita, Retin-A, Retinova, Isotretinoin EP Impurity A CAS No: 302-79-4 Molecular Formula: C20H28O2 Molecular Weight: 300.44 Appearance: Yellow to light orange lyophilized powder. Purity: 98-102% (HPLC) Solubility: Chloroform, DMSO, Methanol (Sparingly) Loss on Drying: 0.5% Melting Point: 168-170°C Sulfated Ash: 0.1% Heavy Metals: 0.002% Limit of Isotretinoin: 5% Storage and Stability: Powder may be stored at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light and temperature sensitive. Keep under inert atmosphere

Product Properties

• Molecular Weight: 300.44
• Purity: 98-102% (HPLC)
• Form: Yellow to light orange lyophilized powder.
• CAS Number: [302-79-4]