Control peptide for S1001-25H. Serotonin plays important physiological functions at the intestinal level, the human intestinal epithelial Caco-2 cells functionally express SERT, both at their apical and basolateral cell membranes. It is a 630aa residue in all human (chr 17q11), rat and mouse and 622aa in Drosophila. it is a multi-pass membrane protein. Serotonin transporter Terminates the action of serotonin by its high affinity sodium-dependent reuptake into presynaptic terminals. Expression is specific to cell bodies in the ventral ganglion of the embryonic and larval nervous system. This protein is the target of psychomotor stimulants such as amphetamines or cocaine. Source: Synthetic peptide corresponding to 20aa of Drosophila SERT, N-terminal, first extracellular domain. Molecular Weight: ~3kD Applications: Suitable for use in ELISA and Antibody Blocking. Not suitable for Western Blot. Other applications not tested. Recommended Dilution: ELISA: 5-10ug control peptide per 1ug of aff pure IgG or 1ul antiserum Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
3
Purity:
Purified
Form:
Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
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