SHH, aa24-197, Recombinant, Human (HHG1, HHG-1, HLP3, HPE3, MCOPCB5, SMMCI, Sonic Hedgehog Protein, TPT, TPTPS)

Catalog Number: USB-S1012-96C
Article Name: SHH, aa24-197, Recombinant, Human (HHG1, HHG-1, HLP3, HPE3, MCOPCB5, SMMCI, Sonic Hedgehog Protein, TPT, TPTPS)
Biozol Catalog Number: USB-S1012-96C
Supplier Catalog Number: S1012-96C
Alternative Catalog Number: USB-S1012-96C-100
Manufacturer: US Biological
Category: Molekularbiologie
SHH, also known as Sonic hedgehog protein, is one of three proteins in the mammalian signaling pathway family called hedgehog. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. It controls cell division of adult stem cells and has been implicated in development of some cancers. Source: Recombinant corresponding to aa24-197 of human SHH 6x his tagged, expressed in E.coli. AA Sequences: MCGPGRGFGK RRHPKKLTPL AYKQFIPNVA EKTLGASGRY EGKISRNSER FKELTPNYNP DIIFKDEENT GADRLMTQRC KDKLNALAIS VMNQWPGVKL RVTEGWDEDG HHSEESLHYE GRAVDITTSD RDRSKYGMLA RLAVEAGFDW VYYESKAHIH CSVKAENSVA AKSGGLEHHH HHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 20.7
NCBI: 000184
Purity: ~95% (SDS-PAGE)
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol, 0.1M sodium chloride.