SREBF2 (Sterol Regulatory Element-binding Protein 2, SREBP-2, Class D Basic Helix-loop-helix Protein 2, bHLHd2, Sterol Regulatory Element-binding Transcription Factor 2, BHLHD2, SREBP2), Rabbit

Product Overview

• Article Name: SREBF2 (Sterol Regulatory Element-binding Protein 2, SREBP-2, Class D Basic Helix-loop-helix Protein 2, bHLHd2, Sterol Regulatory Element-binding Transcription Factor 2, BHLHD2, SREBP2), Rabbit
• Biozol Catalog Number: USB-S6505-18
• Supplier Catalog Number: S6505-18
• Alternative Catalog Number: USB-S6505-18-1
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Immunogen: Synthetic peptide corresponding to aa455-469 from human SREBF2.

Product Description

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5-ATCACCCCAC-3) found in the flanking region of the LDRL and HMG-CoA synthase genes. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 004599
• UniProt: Q12772
• Purity: Purified by affinity chromatography.
• Form: Supplied as a liquid in TBS, 0.1% BSA, 0.02% sodium azide, 50% glycerol.