Substance P (NK, Neurokinin), IgG1, Clone: [SP-DE4-21], Mouse, Monoclonal
Biozol Catalog Number:
USB-S8000-01B
Supplier Catalog Number:
S8000-01B
Alternative Catalog Number:
USB-S8000-01B-10,USB-S8000-01B-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
ELISA, IHC
Immunogen:
Synthetic peptide corresponding RPRPQQFFGLM from human Substance P.
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:10,000 Immunohistochemistry (Vibratome): 1:500-1:1000 Immunohistochemistry (Frozen): 1:300 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
