Alpha Synuclein E46K is a mutant form of alpha synuclein which is changed at position 46 from glutamate (E) to lysine (K). Recent studies have shown that this mutant (E46K) of alpha synuclein causes Parkinson and Lewy Body dementia (DLB). Alpha Synuclein E46K was overexpressed in E. coli. Molecular Weight: 14,459 (Real molecular weight on SDS-PAGE will be shift up) Sequence: MDVFMKGLSK/ AKEGVVAAAE/ KTKQGVAEAA/ GKTKEGVLYV/ GSKTKKGVVH/ GVATVAEKTK/ EQVTNVGGAV/ VTGVTAVAQK/ TVEGAGSIAA/ ATGFVKKDQL/ GKNEEGAPQE/ GILEDMPVDP/ DNEAYEMPSE/ EGYQDYEPEA Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
14459
Purity:
95% by SDS PAGE, Purified to apparent homogeneity by using conventional column chromatography techniques.
Form:
Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 0.1M sodium chloride.
* VAT and and shipping costs not included. Errors and price changes excepted
