Tegafur has been used as an internal standard for the analysis of 5'DFCR (5'deoxyfluorocytidine) and 5'DFUR (5'deoxyfluorouridine) using HPLC techniques[1]. Tegafur has also been used as an internal standard for the chromatographic assay of azidothymidine (AZT). Tegafur is a pro-drug of 5-fluorouracil, an antimetabolite used as an antineoplastic agent. It has been used as adjuvant chemotherapy for curatively resected colorectal cancer therapy. Synonyms: 5-Fluoro-1-(tetrahydro-2-fuanyl)-2,4-(1H,3H)-pyrimidinedione, Citofur, Ftorafur, Exonal, Fental, 5-Fluoro-1-(tetrahydro-2-furyl)uracil, 5-Fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, FT 207, NSC-148958 CAS No: 17902-23-7 Molecular Formula: C8H8FN2O3 Molecular Weight: 200.17 Appearance: White to off-white powder Purity: 98% Melting Point: 167-169C Solubility: DMSO: 40mg/ml, Water: 8mg/ml, Ethanol: 7mg/ml Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
200.17
Purity:
98%
Form:
White to off-white powder
CAS Number:
[17902-23-7]
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