TLR9 (Toll Like Receptor 9, CD289), Rabbit

Product Overview

• Article Name: TLR9 (Toll Like Receptor 9, CD289), Rabbit
• Biozol Catalog Number: USB-T8050-91J
• Supplier Catalog Number: T8050-91J
• Alternative Catalog Number: USB-T8050-91J-100
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC, WB
• Immunogen: Synthetic peptide corresponding to 15aa from an internal region of human TLR9.

Product Description

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 32713
• UniProt: Q9NR96
• Purity: Purified by immunoaffinity chromatography.
• Form: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.