TLR11 (Toll Like Receptor 11), Rabbit
Catalog Number:
USB-T8051-10
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| Article Name: | TLR11 (Toll Like Receptor 11), Rabbit |
| Biozol Catalog Number: | USB-T8051-10 |
| Supplier Catalog Number: | T8051-10 |
| Alternative Catalog Number: | USB-T8051-10-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Immunogen: | Raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11. |
| Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7). Applications: Can be used for detection of TLR11 by Western blot at 0.5-1ug/ml. Storage and Stability: May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20C or colder. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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