TRAIL Receptor 3 (TRAIL R3, TNF-Related Apoptosis Inducing Receptor3), Rabbit

Product Overview

• Article Name: TRAIL Receptor 3 (TRAIL R3, TNF-Related Apoptosis Inducing Receptor3), Rabbit
• Biozol Catalog Number: USB-T8181-15
• Supplier Catalog Number: T8181-15
• Alternative Catalog Number: USB-T8181-15-50,USB-T8181-15-100
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Immunogen: Synthetic peptide corresponding to amino acids from the N-terminal region of human TRAIL R3

Product Description

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 003801
• UniProt: O14798
• Purity: Purified by affinity chromatography.
• Form: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.