Pure human transferrin prepared from pooled normal human serum.
Human Transferrin is an ~80kD blood plasma glycoprotein synthesised by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors. Transferrin is the primary blood iron transport protein and under normal conditions, approximately one-third of total blood Transferrin contains bound iron. Measurement of blood Transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anemia, iron overload and hemochromatosis. Applications: Suitable for use in Immunofluorescence. Other applications not tested. Recommended Dilutions: Optimal dilution to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
