Transferrin is a single polypeptide chain glycoprotein. It is a member of the iron binding family of proteins. It has a MW of 79.5kD. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration range is 1800-2700mg/L. Serum concentration rises in iron deficiency and pregnancy. Serum concentration falls in iron overload, infection and inflammatory conditions. Applications: Suitable for use as a control or standard in ELISA, Western Blot and conjugation. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4C Stable for 6 months after receipt. Store at 4C. Dilute only prior to immediate use.
Molecular Weight:
79.5
Purity:
Purified by delipidation, selective precipitation and dialysis. IEP Assay shows a single precipitin arc against anti-mouse transferrin and anti-mouse serum.
Form:
Supplied as a liquid in 0.01M sodium phosphate buffer, 0.25M sodium chloride, pH 7.6. No preservative and no stabilizing proteins added.
CAS Number:
[11096-37-0]
* VAT and and shipping costs not included. Errors and price changes excepted
