TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Serine/Threonine-protein Kinase Receptor R4, SKR4, Activin Receptor-like

Catalog Number: USB-T8250-31A
Article Name: TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Serine/Threonine-protein Kinase Receptor R4, SKR4, Activin Receptor-like
Biozol Catalog Number: USB-T8250-31A
Supplier Catalog Number: T8250-31A
Alternative Catalog Number: USB-T8250-31A-200
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC, WB
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 134-163 in the central region of human TGFBR1. Species Sequence Homology: bovine, porcine, rat and mouse
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 004603
UniProt: P36897
Purity: Purified by ammonium sulfate precipitation
Form: Supplied as a liquid in PBS, 0.09% sodium azide