TAP2, CT (Antigen Peptide Transporter 2, APT2, Peptide Transporter TAP2, ATP-Binding Cassette Sub-family B Member 3, Peptide Supply Factor 2, Peptide Transporter PSF2, PSF-2, Peptide Transporter Involved In Antigen Processing 2, R
Catalog Number:
USB-T8266-06
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| Article Name: | TAP2, CT (Antigen Peptide Transporter 2, APT2, Peptide Transporter TAP2, ATP-Binding Cassette Sub-family B Member 3, Peptide Supply Factor 2, Peptide Transporter PSF2, PSF-2, Peptide Transporter Involved In Antigen Processing 2, R |
| Biozol Catalog Number: | USB-T8266-06 |
| Supplier Catalog Number: | T8266-06 |
| Alternative Catalog Number: | USB-T8266-06-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC |
| Immunogen: | Synthetic peptide selected from the C-terminal region of human TAP2 (KLH). |
| The membrane-associated protein TAP2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The TAP2 gene is located 7 kb telomeric to gene family member ABCB2. ThTAP2 is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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