TREML2 (Trem-like Transcript 2 Protein, TLT-2, Triggering Receptor Expressed on Myeloid Cells-like Protein 2, Tlt2), IgG2a, Clone: [12K189], Rat, Monoclonal
Biozol Catalog Number:
USB-T8282-40C
Supplier Catalog Number:
T8282-40C
Alternative Catalog Number:
USB-T8282-40C-100
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Application:
FC
Immunogen:
Recombinant corresponding to aa25-270 from mouse TREML2 expressed in CHO-S cell line.
TREML2, also called TLT-2 is a 33kD type I transmembrane cell surface receptor and member of the Trem family of receptor proteins. Mouse TLT-2 is synthesized as a 329aa precursor that contains a 24aa signal sequence, a 246aa extracellular domain (ECD), a 21aa transmembrane segment, and a 38aa cytoplasmic tail. Within the ECD are an Ig-like V-type domain aa25-126 and one potential site for N-linked glycosylation. Mature mouse TLT-2 shares 49% aa sequence identity with mature human TLT-2. Cell surface expression of TLT-2 is seen for most of the B and myeloid cell lines. TLT-2 is also expressed constitutively on CD8+ T cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution:: Flow Cytometry: 2.5ug labels 10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
