5-Trifluorothymidine, CAS [[70-00-8]]

Product Overview

• Article Name: 5-Trifluorothymidine, CAS [[70-00-8]]
• Biozol Catalog Number: USB-T8416-72
• Supplier Catalog Number: T8416-72
• Alternative Catalog Number: USB-T8416-72-100,USB-T8416-72-250,USB-T8416-72-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR (homology-directed repair) efficiency. Synonyms: Trifluridine, Trifluorothymine Deoxyriboside, alpha,alpha,alpha-Trifluorothymidine, 2-Deoxy-5-(trifluoromethyl)uridine, 5-(Trifluoromethyl)-2-deoxyuridine, Viroptic CAS No: 70-00-8 Molecular Formula: C10H11F3N2O5 Molecular Weight: 296.20 Appearance: White crystalline powder Purity: 99.5% (HPLC) Infrared Spectrum: Conforms to structure Loss on Drying: 1% 5-(Trifluoromethyl)uracil: 1% UV Max: 260nm Optical Rotation: [a]D20 = + 49 2 (C=0.3% in H2O) Melting Point: 186-189C Solubility: Methanol (Slightly), DMSO (>25 mg/ml), H2O (>10mg/ml) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 296.2
• Purity: 99.5% (HPLC)
• Form: White crystalline powder
• CAS Number: [70-00-8]