TRIM3 (Tripartite Motif-containing Protein 3, Brain-expressed RING Finger Protein, RING Finger Protein 22, RING Finger Protein 97, BERP, RNF22, RNF97), Goat

Catalog Number: USB-T8464-75E
Article Name: TRIM3 (Tripartite Motif-containing Protein 3, Brain-expressed RING Finger Protein, RING Finger Protein 22, RING Finger Protein 97, BERP, RNF22, RNF97), Goat
Biozol Catalog Number: USB-T8464-75E
Supplier Catalog Number: T8464-75E
Alternative Catalog Number: USB-T8464-75E-100
Manufacturer: US Biological
Host: Goat
Category: Antikörper
Application: ELISA, WB
Immunogen: Synthetic peptide corresponding to AKREDSPGPEVQP-C, from mouse BERP, at N-terminal (NP_006449.2, NP_150594.2).
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the RING-B-box-coiled-coil (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.1-1ug/ml, mouse brain and human brain (cerebellum) observed on ~85kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 006449
Purity: Purified by immunoaffinity chromatography.
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.