TrkA, phosphorylated (Tyr791) (High Affinity Nerve Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 1, TRK1 Transforming Tyrosine Kinase Protein, p140-TrkA, Trk-A, NTRK1, TRK) (Biotin), Rabbit

Product Overview

• Article Name: TrkA, phosphorylated (Tyr791) (High Affinity Nerve Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 1, TRK1 Transforming Tyrosine Kinase Protein, p140-TrkA, Trk-A, NTRK1, TRK) (Biotin), Rabbit
• Biozol Catalog Number: USB-T8663-01D-BIOTIN
• Supplier Catalog Number: T8663-01D-Biotin
• Alternative Catalog Number: USB-T8663-01D-BIOTIN-200
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Immunogen: KLH-conjugated synthetic phosphopeptide mapping to a fragment of residues surrounding Tyr791 of human TrkA, UniProt Accession P04629

Product Description

TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Product Properties

• NCBI: 002520
• UniProt: P04629
• Purity: Purified by protein A affinity chromatography.
• Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.