Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins. It is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. This expression in the human heart is affected by heart failure. Applications: Suitable for use in ELISA and immunoaffinity purification. Other applications not tested. Recommended Dilutions: ELISA: Sandwich Optimal dilutions to be determined by the researcher. Recommended Pair: Capture: T8665-22C Detection: T8665-30A Hybridoma: Sp2/0 myeloma cells with spleen cells of Balb/c mice Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[5E843]
Isotype:
IgG2b
Purity:
Purified by Protein A Sepharose chromatography from ascites
Form:
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
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