Tumor Necrosis Factor alpha, Clone: [3H3097 MP6-XT3], Rat, Monoclonal
Biozol Catalog Number:
USB-T9160-13G
Supplier Catalog Number:
T9160-13G
Alternative Catalog Number:
USB-T9160-13G-500
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Application:
ELISA
Immunogen:
Recombinant protein corresponding to mouse TNF-alpha, expressed in E. coli.
Tumor Necrosis Factor alpha (TNF-alpha) is a 17.3kD multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts. TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-KappaB, the induction of apoptosis in various tumor cell lines and the stimulation of cell differentiation and proliferation under certain conditions. Studies have revealed a role for TNF-alpha in inflammation, septic shock, autoimmune disease and rheumatoid arthritis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
