Tyrosine Hydroxylase (TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase) (MaxLight 490), Rabbit
Catalog Number:
USB-T9237-10L-ML490
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| Article Name: | Tyrosine Hydroxylase (TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase) (MaxLight 490), Rabbit |
| Biozol Catalog Number: | USB-T9237-10L-ML490 |
| Supplier Catalog Number: | T9237-10L-ML490 |
| Alternative Catalog Number: | USB-T9237-10L-ML490-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IHC, WB |
| Immunogen: | Recombinant protein corresponding to mouse Tyrosine Hydroxylase at C-terminus. |
| MaxLight(TM)490 is a new Blue-Green photostable dye conjugate comparable to DyLight(TM)488, Alexa Fluor(TM)488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm), Emission (515nm), Extinction Coefficient 73,000. Tyrosine Hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry (Paraffin): 1:100 Optimal dilutions to be determined by the researcher. Positive Control: Rat brain lysate Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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