Tyrosyl tRNA synthetase, CT (YARS, CMTDIC, TYRRS, YRS, YTS), Rabbit

Catalog Number: USB-T9248-87G
Article Name: Tyrosyl tRNA synthetase, CT (YARS, CMTDIC, TYRRS, YRS, YTS), Rabbit
Biozol Catalog Number: USB-T9248-87G
Supplier Catalog Number: T9248-87G
Alternative Catalog Number: USB-T9248-87G-200
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC, WB
Immunogen: Synthetic peptide selected from the C-terminal region of human YARS (KLH).
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 003671
UniProt: P54577
Purity: Purified by ammonium sulfate precipitation.
Form: Supplied as a liquid in PBS, 0.09% sodium azide.