Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide), CAS [[134036-52-5]]

Product Overview

• Article Name: Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide), CAS [[134036-52-5]]
• Biozol Catalog Number: USB-T9250-15
• Supplier Catalog Number: T9250-15
• Alternative Catalog Number: USB-T9250-15-25
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth, induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Chemical Name: N-benzyl-3,4-dihydroxybenzylidenecyanoacetamide Chemical Family: Aromatic nitrile Solubility: Soluble in DMSO Melting Point: 215-216.5C Storage (unopened): Store at or below 4C in the dark.

Product Properties

• Molecular Weight: 294.31
• Purity: ~99%, by HPLC
• Form: Off-white to tan lyophilized powder
• CAS Number: [134036-52-5]